Streptococcus mutans JC-2의 우식활성에 미치는 가자의 효과
Effect of 'Terminalia Chebula Retz.' on the Dental Caries Activity of Streptococcus mutans JC-2
남용옥, 김선숙, 장윤정,
소속 상세정보
남용옥 ( ) - 원광보건전문대
김선숙 ( ) - 원광보건전문대
장윤정 ( ) - 원광보건전문대
KMID : 0355419950190040495
Abstract
In order to develop natural sources which prevent dental caries, we investigated the effects of Terminalia chebula Retz. on the groeth, acid production, membrane permeability and glucosyltransferase(GTase)of Streptococcus mutans JC-2 in broth
system.
The water and methanol extract of Terminalia chebula Retz. showed antimicrobial activity against S.mutans JC-2 in broth system. Especially, its water extract had the most significant inhibithion activity at 1000 and 2000ppm of concentration.
The water extract of Terminalia chebula Retz. inhibited the activity of GTase and then showed 40.2, 43.3 and 78.8% inhibition rate at 500, 1000 and 2000ppm of concentration, respectively. Also its methanol extract showed 40.2, 83.8 and 91.9%
repectively.
The amount of leakaged cytosolic companents of S.mutans JC-2 increased according to the concentration of Terminalia chebula Retz.
키워드
원문 및 링크아웃 정보
등재저널 정보